Turner International to Cut Staff in Europe, Middle East, Africa - The ...

Alexander Tamargo/Getty Images

LONDON -- Time Warner's Turner Broadcasting System International unit said Tuesday that it plans to cut about 30 percent of the staff in its Europe/Middle East/Africa (EMEA) business as part of a restructuring that will give more power to regions and cut back on central functions.

The company's overall EMEA business includes about 900 positions, so about 250-plus positions are expected to be eliminated in the restructuring.
?
Gerhard Zeiler, president of TBS International, unveiled the organizational shake-up. "Some functions, which can be handled externally at the same quality, will be outsourced," the company said. It didn't detail the annual savings from the cuts.

Turner International said it anticipates the 30 percent reduction in positions across the EMEA business to become effective upon completion of a consultation process with staff representatives. "This estimation comprises open headcount, positions that became vacant and are not being reoccupied, redundancies and outsourcing," it said without detailing the likely timing of the moves.
?
The decisions are part of a review process for its EMEA business that Turner International launched in September.

?This review required us taking some tough decisions, but they are absolutely necessary to put Turner International in the best possible position for future growth,? said Zeiler. ?Greater empowerment and broader accountability for local management will lead to simplified processes throughout the organization, improved efficiency and reduced costs.?
?
Turner Broadcasting System International operates more than 100 channels that are versions of core Turner brands, such as CNN, TNT, Cartoon Network and Turner Classic Movies, in more than 30 languages in 200 countries around the world. Turner's EMEA business has 17 branded channels in 27 languages in more than 100 territories.

Email: Georg.Szalai@thr.com

Twitter: @georgszalai
?

Source: http://www.hollywoodreporter.com/news/turner-international-cut-staff-europe-412616

buckyballs awake mario batali lone ranger aaron brooks dave matthews band solar flares 2012

Stepparenting & Blended Families 2013: Stepmonster: A New Look ...

Buy on the merchant's online shopping and scan reviews. If you're attempting to seek out Stepmonster: A New Look at Why Real Stepmothers Think, Feel, and Act the Way We Do with special price. This is the most effective deals for you. Where you could realize these item is by on-line shopping stores? Read the review on Stepmonster: A New Look at Why Real Stepmothers Think, Feel, and Act the Way We Do Now, it's the simplest deal. Thus don't lose it.

Stepmonster: A New Look at Why Real Stepmothers Think, Feel, and Act the Way We Do
by Wednesday Martin
(85)

New!: $25.00 $16.50 (as of 01/15/2013 21:54 PST)
60 Used! | New! from $13.01 (as of 01/15/2013 21:54 PST)

Stepparenting & Blended Families

An honest and groundbreaking guide to understanding the complicated emotions that develop between stepmothers and children.

?

When faced with often overwhelming challenges, what woman with stepchildren is unfamiliar with that ?stepmonster? feeling? Half of all women in the United States will live with or marry a man with children. To guide women new to this role?and empower those who are struggling with it?Wednesday Martin draws upon her own experience as a stepmother. She's frank about the harrowing process of becoming a stepmother, she considers the myths and realities of being married to a man with children, and she counteracts the cultural notion that stepmothers are solely responsible for the problems that often develop. Along the way, she interviews other stepmothers and stepchildren and offers up fascinating insights from literature, anthropology, psychology, and evolutionary biology that explain the little-understood realities of this unique parent-child relationship and?in an unexpected twist?shows why the myth of the Wicked Stepmother is the single best tool for understanding who real stepmothers are and how they feel.

?

• Rank: #34268 in Books
• Published on: 2009-05-04
• Original language: English
• Number of items: 1
• Dimensions: 1.10" h x 6.20" w x 9.00" l, 1.05 pounds
• Binding: Hardcover
• 336 pages

Source: http://hotstepparentingblendedfamilies583.blogspot.com/2013/01/stepmonster-new-look-at-why-real.html

terminator salvation deron williams jarhead montrose marshawn lynch earthquake bay area clear channel

Another Day, Another Accident ? New York Personal Injury Law Blog

Car accident, Nov 21, 2012

First off, let me say this: No one was hurt. Regular readers know that I don?t generally write about local car accidents ? unless there is an appellate decision or something legally noteworthy about them. But this was an accident that my family was in.

It was the Wednesday before Thanksgiving, and I was in the front passenger seat with Mrs. NYPILB behind the wheel. We made a right at a light from one main road to another. And out of a parking area on our right came an SUV trying to cross the road. Presumably to get to the other side.

Except that we were passing in front of him; and he t-boned us. Right into the passenger side, with the brunt of the force on the back door where my son was sitting, engrossed in a book.

There are several things that might race through the brain at this point, of which these are three:

1. The Parent (Are my kids OK, and how do we make sure there is no further potential for accident or injury?)

2. The Lawyer (The other driver failed to yield the right of way)

3. ?The bureaucrat (Closely linked to the lawyer, this one seeks documentation to make sure that the ?i?s are dotted and the ?t?s crossed with respect to insurance companies.)

Now this is ?not the first time I?ve written about an accident that I was in. It happened five years ago when a car with no lights and no license plates stopped in the middle of the parkway at night. I was driving and I stopped in time. One of the cars behind me did not.

The view of the inside, with the door closed, where my son was sitting

And you know what? I?m no better prepared today for being in an accident than I was back then; because accidents are unexpected. If we expected them, well, we have a better chance of avoiding them.

Because they are unexpected, we often don?t really know, at the time of the impact, the answers to the questions that may one day flow if someone was really injured and an investigation or lawsuit ensued.

How fast were you going?

What lane where you in? (How many lanes were there?)

Where did you look in the seconds before the accident?

Where, exactly, ?were you?

While that last question might seem a bit silly, it really isn?t, most especially if it is a highway that you have driven ?hundreds of times. Your brain might well be on auto-pilot and while you know generally where you are, the exact location isn?t something that you were keyed in to. You might know, for example, that you needed exit 56, and that you were somewhere around exit 30, give or take. You don?t know exactly, because it isn?t particularly relevant.

The reality is that most of our ?recollection? of an accident is our brain reconstructing what has happened as we spin our heads around and say WTF? And when we reconstruct things, we tend to fill in the blanks. This is a mental process that I like to refer to has ?normal human behavior.? The psychs like to call it reconstructed memory, and will tell you that the brain abhors a vacuum so it provides the filler it believes to be logical.

But it?s odd when your own brain may be doing the the reconstructing, not someone else?s.

This fill-in-the-blanks view of an accident will generally lead to conflicting accounts of an event. People see things through the prism of their own experiences, both past and present and upon review of the event that just took place, and fill in the missing blanks. We may now see mileposts and exit markers, when before we were just driving merrily along knowing that we were roughly 15 minutes from our exit and keeping an eye on the car in front of us. We see intersections and people (aka witnesses) that we hadn?t really noticed or appreciated before. Because the accident, almost by definition, happened very fast and we had no time to react.

And, of course, the adrenal gland has decided that this would be a magnificent time to give the body a good old shot of hormone that sends the heart and mind racing.

After an accident, nothing is normal at all. But that moment when the mind and body are reeling is the moment the brain is imprinted with the ?details? of recollection. Since those recollections are experienced through the prisms of our own histories, the lawyer might well ?see? something different in an accident than the doctor, mechanic or cop.

All of this is something that the reader likely already knows, on an intellectual level. And yet, when one actually goes through the event, it doesn?t really matter. The god?s eye view of what happened ? that fly on the wall view of things ? may well be distorted by emotion, by experience and by reconstruction.

I wrote this post six weeks ago and have been sitting on it ever since, hoping I could come up with some kind of snappy conclusion or insight. But I can?t, other than to say that the most important thing is immediate safety. For us, sitting in the roadway after the accident near a busy intersection, that mean moving the car immediately out of danger into the parking area where the offending SUV came from.

I remember my father telling me, when I was learning to drive some 35 years ago, that if I got a flat tire on a bridge that I should not stop. Drive it off the bridge, and to hell with any additional damage to the car. It is, after all, just a car.

Safety first.

Tags:

Source: http://www.newyorkpersonalinjuryattorneyblog.com/2013/01/another-day-another-accident.html

new nfl uniforms easter derbyshire the matrix oceans 11 ferris state hockey mary poppins

Guernsey personal trainer: Questions but no answers | Storm Force ...

Have you stopped asking questions?

Have you accepted that the fitness industry is failing you?

Do you really just want something to do of an evening?

Do you just want to pay for a diet that makes you feel a bit better about yourself but makes you track points, count calories and let?s you get away with so much destructive behaviour that you never get anywhere?

I understand why you might feel like this.

80% of gym users don?t get the results they want and but nobody ever speaks up because nobody else is getting results so it?s easy to think you?re just not one of the ?lucky? ones who happens to get results.

You don?t get lucky with fitness and fat loss.

Either the system you are following works or it doesn?t.

If it doesn?t, chances are you?re not following it properly but nobody is questioning YOU.

See the problem is that you don?t ask enough questions.

There?s an old interrogation principle that goes?.

?Ask enough questions and the man who is lying will eventually change his story?.

You should try applying this to those who you entrust your health and fitness.

Keep asking the owner and trainers in your gym what?s the best way to get the results YOU want.

Let?s say you want to lose fat fast and keep it off, and you keep asking me this question.

95% of the answers I will give you will be no different to what I would have said 10 years ago.

3-4 sessions per week combining strength work, dynamic sets and conditioning circuits.

Increase time under tension when lifting weights.

Drink lots of water.

Ensure most meals are protein, fats and vegetables.

Cycle carbohydrates so you keep your thyroid buzzing whilst optimising the conditions for fat burning.

Take a protein shake in after training.

Get enough sleep.

Manage your stress.

Throw in 1-2 fasting periods each week.

If finances permit, get your hormones tested.

Build your health and watch fat loss happen faster than you ever imagined.

Now imagine you had asked your commercial gym what was the best way to lose fat every year for the last 10 years.

The answers will have changed every 5 minutes.

Aerobics.

Machine based workouts for a while.

Long cardio sessions this year.

BodyPump now.

Hula hoop classes.

Zumba this time.

Flying around on straps is the latest thing.

Remember?.

?Ask enough questions and the man who is lying will eventually change his story?.

Every year, the gym will change their mind on what to recommend based not on what delivers results, but what entertains people and gives them another spark of hope that there might be some new, magic class which really does solve everything this year.

Then you ask the question again and they change their story.

Look at the places in the world where life span is the longest.

They are doing the same things they did hundreds of years ago!

Clean food, fresh air, regular exercise, low stress levels.

The story NEVER changes and they laugh at all the modern fads that come along.

It?s like the tortoise and the hare.

In three years of the Storm Force Fitness Academy, very little has changed in what I have recommended.

Occasionally I find a way to simplify something but there?s another saying that goes?.

?Methods are many, principles are few. Methods often change, principles never do?.

The principles of fat loss NEVER change. The man who knows fat loss, will never change his story.

How often do journalists change their story on the best diet?

How often does the ?know it all? in the office, change the diet they are on then try to convince you ?this is the one??

How often do certain people switch personal trainers?

Yeah that?s right.

Not only are you being lied TO by the commercial areas of the health and fitness industry, but you may also be lying to yourself.

If you have not yet taken the time to deeply question YOURSELF about how you want to look, who you want to be and how you want to feel, you will keep lying to YOURSELF.

?He who stands for nothing falls for anything.?

Ask yourself this question.

Who would you rather be in this image below if you HAD to choose?

What do you REALLY believe in?

What person are you really deep down?

Don?t shirk the question!!!!

YOU HAVE TO CHOOSE NOW.

YOU HAVE TO BE ONE PERSON IN THE PHOTO.

Do you say one thing about who you are and what you believe then change your mind when the sh*t hits the fan?

It?s not about being a martyr but it IS about questioning whether you are just a puppet to circumstance and environment.

Are you a marketers dream?

Are you controlled by ?instant coffee? reactions to some clever jedi mind tricks that get you excited for the next big thing?

Now don?t get me wrong.

I accept my part in your life as the guy who must provide answers.

All I ask is that you start to ask the right questions of both myself and anyone else you seek help from.

Pay attention and find out whether their belief is strong enough in what they offer or if they will change tracks more often than a train with no driver.

Ask the questions and when you find someone with so much heart and so much belief in what they do because it has been proven over and over again, commit to it.

Do it properly.

Give it everything.

Believe you deserve more.

And when you believe as much as they do, you will no longer have so many questions buzzing around your head just making your life even more confusing and you?ll no longer be an ?Askhole??.

Fat loss really is quite simple, but we make it complicated by not asking enough of the right questions.

We just keep handing over money.

We just keep spending our time getting nowhere.

The money you can get back.

The time, you cannot.

Start asking questions of yourself and those who should be serving you.

I mean REALLY serving you.

Source: http://guernseypersonaltrainer.com/2013/01/question/

think like a man world peace world peace lakers colorectal cancer metta kashi neil diamond

Multiple sclerosis study reveals how killer T cells learn to recognize nerve fiber insulators

Multiple sclerosis study reveals how killer T cells learn to recognize nerve fiber insulators

Monday, January 14, 2013

Misguided killer T cells may be the missing link in sustained tissue damage in the brains and spines of people with multiple sclerosis, findings from the University of Washington reveal. Cytoxic T cells, also known as CD8+ T cells, are white blood cells that normally are in the body's arsenal to fight disease.

Multiple sclerosis is characterized by inflamed lesions that damage the insulation surrounding nerve fibers and destroy the axons, electrical impulse conductors that look like long, branching projections. Affected nerves fail to transmit signals effectively.

Intriguingly, the UW study, published this week in Nature Immunology, also raises the possibility that misdirected killer T cells might at other times act protectively and not add to lesion formation. Instead they might retaliate against the cells that tried to make them mistake the wrappings around nerve endings as dangerous.

Scientists Qingyong Ji and Luca Castelli performed the research with Joan Goverman, UW professor and chair of immunology. Goverman is noted for her work on the cells involved in autoimmune disorders of the central nervous system and on laboratory models of multiple sclerosis.

Multiple sclerosis generally first appears between ages 20 to 40. It is believed to stem from corruption of the body's normal defense against pathogens, so that it now attacks itself. For reasons not yet known, the immune system, which wards off cancer and infection, is provoked to vandalize the myelin sheath around nerve cells. The myelin sheath resembles the coating on an electrical wire. When it frays, nerve impulses are impaired.

Depending on which nerves are harmed, vision problems, an inability to walk, or other debilitating symptoms may arise. Sometimes the lesions heal partially or temporarily, leading to a see-saw of remissions and flare ups. In other cases, nerve damage is unrelenting.

The myelin sheaths on nerve cell projections are fashioned by support cells called oligodendrocytes. Newborn's brains contain just a few sections with myelinated nerve cells. An adult's brains cells are not fully myelinated until age 25 to 30.

For T cells to recognize proteins from a pathogen, a myelin sheath or any source, other cells must break the desired proteins into small pieces, called peptides, and then present the peptides in a specific molecular package to the T cells.

Scientists had previously determined which cells present pieces of a myelin protein to a type of T cell involved in the pathology of multiple sclerosis called a CD4+ T cell. Before the current study, no cells had yet been found that present myelin protein to CD8+ T cells.

Scientists strongly suspect that CD8+ T cells, whose job is to kill other cells, play an important role in the myelin-damage of multiple sclerosis. In experimental autoimmune encephalitis, which is an animal model of multiple sclerosis in humans, CD4+ T cells have a significant part in the inflammatory response. However, scientists observed that, in acute and chronic multiple sclerosis lesions, CD8+T cells actually outnumber CD4+ T cells and their numbers correlate with the extent of damage to nerve cell projections. Other studies suggest the opposite: that CD8+T cells may tone down the myelin attack.

The differing observations pointed to a conflicting role for CD8 + T cells in exacerbating or ameliorating episodes of multiple sclerosis. Still, how CD8+T cells actually contributed to regulating the autoimmune response in the central nervous system, for better or worse, was poorly understood.

Goverman and her team showed for the first time that naive CD8+ T cells were activated and turned into myelin-recognizing cells by special cells called Tip-dendritic cells. These cells are derived from a type of inflammatory white blood cell that accumulates in the brain and the spinal cord during experimental autoimmune encephalitis originally mediated by CD4+ T cells. The membrane folds and protrusions of mature dendritic cells often look like branched tentacles or cupped petals well-suited to probing the surroundings.

The researchers proposed that the Tip dendritic cells can not only engulf myelin debris or dead oligodendrocytes and then present myelin peptides to CD4 + T cells, they also have the unusual ability to load a myelin peptide onto a specific type of molecule that also presents it to CD8+ T cells. In this way, the Tip dendritic cells can spread the immune response from CD4+ T cells to CD8+ T cells. This presentation enables CD8+ T cells to recognize myelin protein segments from oligodendrocytes, the cells that form the myelin sheath. The phenomenon establishes a second-wave of autoimmune reactivity in which the CD8+ T cells respond to the presence of oligodendrocytes by splitting them open and spilling their contents.

"Our findings are consistent," the researchers said, "with the critical role of dendritic cells in promoting inflammation in autoimmune diseases of the central nervous system." They mentioned that mature dendritic cells might possibly wait in the blood vessels of normal brain tissue to activate T-cells that have infiltrated the blood/brain barrier.

The oligodendrocytes, under the inflammatory situation of experimental autoimmune encephalitis, also present peptides that elicit an immune response from CD8+T cells. Under healthy conditions, oligodendrocytes wouldn't do this.

The researchers proposed that myelin-specific CD8+T cells might play a role in the ongoing destruction of nerve-cell endings in "slow burning" multiple sclerosis lesions. A drop in inflammation accompanied by an increased degeneration of axons (electrical impulse-conducting structures) coincides with multiple sclerosis leaving the relapsing-remitting stage of disease and entering a more progressive state.

Medical scientists are studying the roles of a variety of immune cells in multiple sclerosis in the hopes of discovering pathways that could be therapeutic targets to prevent or control the disease, or to find ways to harness the body's own protective mechanisms. This could lead to highly specific treatments that might avoid the unpleasant or dangerous side effects of generalized immunosuppressants like corticosteroids or methotrexate.

###

University of Washington: http://www.uwnews.org

Thanks to University of Washington for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 34 time(s).

Source: http://www.labspaces.net/126256/Multiple_sclerosis_study_reveals_how_killer_T_cells_learn_to_recognize_nerve_fiber_insulators

blake griffin pau gasol marlins park marbury v. madison 2013 lincoln mkz burger king mary j blige google project glass

Tweeting Cat Door Keeps Unauthorized Animals Out of Your Home

If you've ever had a stray cat come in your pet door at night, you know that event usually leads to shenanigans. If you have the time and funds you can construct a secure pet door that only lets your cat or dog in after scanning the RFID tag on a pet collar, taking a webcam photo of your pet entering or exiting, and tweeting the event.

This project started as an Instructable from user e1ioan, but has now grown so popular that e1ioan has created a site for the project and offers kits for those who are lazy or uncomfortable with soldering.

It isn't a cheap project?you'll need a RFID reader, a micro server to act as a latch control, a webcam, a router running Open WRT, and several semiconductors, capacitors, resistors, and other electrical hardware as well as a flap-type pet door. From a quick look online the budget for this project seems to be in the $100-150 range if you do everything yourself. The source link below offers loads of schematics, step-by-step instructions, and the complete code needed for the project. But if you're a techy pet-lover this might be for you.

Tweeting Cat Door | via Instructables

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/SXFUF2gwtfI/tweeting-cat-door-keeps-unauthorized-animals-out-of-your-home

joseph kony joseph kony ipad 3 release date apple store down apple live blog ohio primary cell phone jammer

iphone Music Game "Crayon Sax"

Posting Rules You may not post new threads You may not post replies You may not post attachments You may not edit your posts HTML code is Off

iPhone Game Reviews | iPhone Apps

All times are GMT -5. The time now is 03:19 PM.

Source: http://forums.toucharcade.com/showthread.php?t=174276&goto=newpost

Jacintha Saldanha Grammy nominations 2013 Butch Jones thursday night football japan earthquake Star Trek Into Darkness Heisman watch